Articles matching the ‘Cardiovascular risk’ Category

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November 9th, 2015

Podcast 189: Blood Pressure Target Should Be 120, SPRINT Data Show

The SPRINT study, suggesting that we aim for a systolic BP target of 120 mm Hg in high-risk hypertensive patients, has been published with much fanfare. Dr. Paul Whelton — one of the SPRINT investigators — is our guest. He warns against setting 120 as a performance measure, observing that roughly half the patients in the […]


August 16th, 2015

Podcast 182: Dietary fat studies meta-analyzed — trans fat still a bad bet

The BMJ’s meta-analysis of several large cohorts finds no association of saturated fat with all-cause and cardiovascular mortality or total coronary disease. Trans fat, on the other hand, increased risk in all those categories. The first author on the paper, Dr. Russell de Sousza, isn’t ready to give a free pass to saturated fat, though. Listen […]


August 29th, 2014

Podcast 173: Sensible Sodium Levels in View at Last

Running time: 9 minutes In the light of the New England Journal of Medicine‘s recent publication three papers on sodium intake and its implications for cardiovascular disease, blood pressure, and excess mortality, we thought we’d speak again with Dr. Jan Staessen, who surprised a lot of people 3 years ago with a paper in JAMA warning […]


November 12th, 2013

Podcast 169: New guidelines on cardiovascular disease prevention

 Running time: 11 minutes The American Heart Association/American College of Cardiology have released four sets of guidelines — all aimed at the lowering of risk for atherosclerotic cardiovascular disease. For perspective, we’ve asked Harlan Krumholz, editor-in-chief of NEJM Journal Watch Cardiology and CardioExchange to chat. Links: Risk calculator (free) CardioExchange (free) Circulation homepage New York Times piece by Krumholz on […]


September 14th, 2013

Podcast 167 — The polypill: adherence at last?

Running time: 7 min The recent JAMA article examining the effects of the “polypill” on adherence and clinical benefits in patients with (or at high risk for) cardiovascular disease, is our topic. The polypill in this trial contained fixed doses of four separate drugs: aspirin, a statin, lisinopril and one other blood-pressure-lowering drug — either atenolol […]


February 13th, 2012

Podcast 145: The Y chromosome and the possible role of a common variant in coronary disease in men.

Haplogroups — who knew? Ancient variations in the Y chromosome form what’s known as haplogroups, and haplogroup I is common in Europe, particularly so in northern Europe. Researchers find that “I” is an independent risk factor for coronary artery disease in men, carried as it is on the male-only Y chromosome. Listen in as we talk […]


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