Articles matching the ‘stroke’ Category

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February 18th, 2016

Podcast 195: Pioglitazone for secondary prevention?

Pioglitazone, long known to increase insulin sensitivity, has been “mostly relegated to use in unusual conditions such as lipodystrophies” after its drug class, the thiazolidinediones, “fell from grace” in the words of our guest. Dr. Clay Semenkovich has just written an editorial comment on a study in the New England Journal of Medicine. That study […]


November 12th, 2013

Podcast 169: New guidelines on cardiovascular disease prevention

 Running time: 11 minutes The American Heart Association/American College of Cardiology have released four sets of guidelines — all aimed at the lowering of risk for atherosclerotic cardiovascular disease. For perspective, we’ve asked Harlan Krumholz, editor-in-chief of NEJM Journal Watch Cardiology and CardioExchange to chat. Links: Risk calculator (free) CardioExchange (free) Circulation homepage New York Times piece by Krumholz on […]


August 15th, 2013

Podcast 165: The Mediterranean diet’s salutary interaction with risk-conferring genes

Running time: 14 minutes. A study in Diabetes Care shows that people at higher genetic risk for diabetes and cardiovascular complications had a relatively lower stroke risk when they adhered to a Mediterranean diet. Dr. Jose Ordovas, the study’s senior author, is our guest for this discussion about the interaction between genes and diet — and […]


March 29th, 2012

Podcast 150: Depression (and antidepressant use) after stroke or TIA

After stroke or transient ischemic attack, depression is more common than among the general population, and the risk for depression extends beyond the early time period after the event. More alarmingly, less than a third of those with persistent depression — defined as depression detected both at 3 and 12 months after the cerebrovascular event — […]


January 13th, 2012

Podcast 141: Clinically apparent atrial fibrillation increases stroke risk; does subclinical afib do the same?

Yes, it apparently does. An international study in the New England Journal of Medicine monitored subclinical atrial fibrillation among some 2600 patients who’d just received an implanted pacemaker or cardioverter-defibrillator. After 3 months of monitoring, about 10% of the group showed subclinical episodes of afib lasting at least 6 minutes. Over an additional 2.5 years of follow-up the […]


March 10th, 2011

Podcast 115: Talking about the real-world use of dabigatran with Drs. Elaine Hylek and Samuel Goldhaber

Clinical Conversations, in a collaboration with CardioExchange, has interviewed two expert working clinicians on how best to use dabigatran — a drug poised to supplant warfarin in the prevention of stroke and systemic embolism in patients with atrial fibrillation. The wide ranging discussion with Drs. Elaine Hylek and Samuel Goldhaber  includes sections on who should be […]


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