August 16th, 2019
Podcast 229: Simplifying perioperative anticoagulation in AF
Patients with atrial fibrillation who undergo surgical procedures need special attention because their anticoagulant medications, if not adjusted, increase their risk for bleeding. Those on direct-acting oral anticoagulants — or “DOACs” — face special problems because assays for the amount of drug on-board before surgery are not routinely available. Dr. James Douketis and international colleagues have […]
October 10th, 2017
Podcast 214: Drug-drug interactions and bleeding risks with NOACs
The non-vitamin-K oral anticoagulants (known familiarly as NOACs or DOACs) share metabolic pathways with other drugs, which can potentiate NOACs’ anticoagulant actions dangerously. Dr. Shang-Hung Chang and his group studied Taiwan’s national health insurance database, which records data on virtually all that nation’s citizens, to measure the actual risks of some of these drug – […]
July 11th, 2015
Podcast 179: Pradaxa (dabigatran) reversal near?
Running time: 20 minutes The anticoagulant dabigatran, marketed in the U.S. as Pradaxa, has always had the problem that, although it’s more convenient to use, there’s no sure way to stop its effect if the patient has a major bleed. Now, a monoclonal antibody fragment called idarucizumab (pronounced i-DARE-you-scis-ooh-mab) shows promise as a reversal agent. In an […]
March 10th, 2011
Podcast 115: Talking about the real-world use of dabigatran with Drs. Elaine Hylek and Samuel Goldhaber
Clinical Conversations, in a collaboration with CardioExchange, has interviewed two expert working clinicians on how best to use dabigatran — a drug poised to supplant warfarin in the prevention of stroke and systemic embolism in patients with atrial fibrillation. The wide ranging discussion with Drs. Elaine Hylek and Samuel Goldhaber includes sections on who should be […]
December 17th, 2010
Podcast 111: A look back on the year’s most clinically important developments.
Dr. Danielle Scheurer and Joe Elia have a free-form discussion on what’s happened over the past year. Links to those stories (and, sometimes, interviews) are attached here. If you’d like to suggest another, or comment on our selection, drop us a note in the comments field. Discussion-related links (they are all free links): Rivaroxaban Dabigatran Screening for lung cancer […]
October 22nd, 2010
Podcast 105: NSAIDs revisited
In the face of scheduling problems we’ve had to postpone this week’s interview and use, instead, one from early this summer. It’s on NSAIDs, and if you missed it, it’s worth a listen. If you didn’t miss it, then join us again next week, but give a listen to the news round-up before you head […]
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