August 16th, 2019
Podcast 229: Simplifying perioperative anticoagulation in AF
Patients with atrial fibrillation who undergo surgical procedures need special attention because their anticoagulant medications, if not adjusted, increase their risk for bleeding. Those on direct-acting oral anticoagulants — or “DOACs” — face special problems because assays for the amount of drug on-board before surgery are not routinely available. Dr. James Douketis and international colleagues have […]
March 9th, 2018
Podcast 217: Aspirin and rivaroxaban “comparably effective and safe” for prophylaxis after arthroplasty
The EPCAT II trial examined whether aspirin and rivaroxaban were clinically equivalent in the extended prophylaxis of venous thromboembolism after hip or knee replacement. They proved “comparably effective and safe,” according to our guest, Dr. David Anderson, the study’s first author. An editorial in the New England Journal of Medicine, where the study appeared in […]
October 10th, 2017
Podcast 214: Drug-drug interactions and bleeding risks with NOACs
The non-vitamin-K oral anticoagulants (known familiarly as NOACs or DOACs) share metabolic pathways with other drugs, which can potentiate NOACs’ anticoagulant actions dangerously. Dr. Shang-Hung Chang and his group studied Taiwan’s national health insurance database, which records data on virtually all that nation’s citizens, to measure the actual risks of some of these drug – […]
December 17th, 2010
Podcast 111: A look back on the year’s most clinically important developments.
Dr. Danielle Scheurer and Joe Elia have a free-form discussion on what’s happened over the past year. Links to those stories (and, sometimes, interviews) are attached here. If you’d like to suggest another, or comment on our selection, drop us a note in the comments field. Discussion-related links (they are all free links): Rivaroxaban Dabigatran Screening for lung cancer […]
November 19th, 2010
Podcast 109: An overview of the American Heart Association meeting, with cardiologist Harlan Krumholz
We’ve got Dr. Harlan Krumholz, editor of Journal Watch Cardiology and CardioExchange, to guide us through a week’s worth of the top research presented at the American Heart Association in Chicago. Interview-related links (in the order we discuss them in the interview): CardioExchange (worth checking out — it’s an experiment in the clinical use of social media) […]
June 27th, 2008
Podcast 5: News and interview with Dr. Jack Hirsh, Professor Emeritus, Dept of Medicine, McMaster and Founding Director of the Henderson Research Centre, Hamilton Ontario
Jack Hirsh discusses the American College of Chest Physicians’ new guidelines on antithrombotic and thrombolytic therapy. Home blood pressure monitoring http://general-medicine.jwatch.org/cgi/content/full/2008/624/2 Depression and diabetes http://psychiatry.jwatch.org/cgi/content/full/2008/623/2 http://firstwatch.jwatch.org/cgi/content/full/2008/618/1 Stroke risk http://firstwatch.jwatch.org/cgi/content/full/2008/624/1 Rivaroxaban http://oncology-hematology.jwatch.org/cgi/content/full/2008/625/1
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