Posts Tagged ‘cardiovascular disease’

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November 1st, 2019

Podcast 240: Overuse of statins for primary prevention of cardiovascular events

Running time: 23 minutes Paula Byrne set out to understand what the available data tell us about how many people are taking statins for primary prevention — and how much good is it likely doing them? Also, how do you discuss their possible harms and benefits with patients? Links: Paula Byrne and colleagues’ analysis in The BMJ Kausik Ray […]


September 9th, 2014

Podcast 174: PARADIGM and Heart Failure

The PARADIGM-HF trial of LCZ696 — a novel compound that both blocks the renin-angiotensin system with an ARB component and blocks neprilysin’s degradation of natriuretic peptides — increased survival in heart failure by some 20% relative to enalapril. It seems to be a big deal, and the trial’s two principal authors have agreed to talk […]


December 5th, 2009

Podcast 68: Change your approach to pharyngitis in adolescents and young adults.

Dr. Robert Centor of the University of Alabama at Birmingham believes that the paradigm for treating pharyngitis in adolescents and young adults must change. Listen to our conversation and hear why. Here are this week’s links: Interview: Commentary Urges ‘Expanding the Diagnostic Paradigm of Pharyngitis’ in Young People Robert Centor’s blog — “Medrants” News stories: Chronic Pain Linked […]


July 2nd, 2009

Podcast 48: A conversation with Les Irwig, which your bone scanner won’t like to hear.

Scanning patients on bisphosphonates within the first 3 years of therapy is just wasted effort, and may even be misleading clinically. That’s what researchers conclude after reanalysis of FIT trial data on some 6500 women taking either alendronate or placebo. Prof. Les Irwig of the University of Sydney talks about his team’s findings and what […]


May 8th, 2009

Podcast 42: An interview with Danielle Ofri — author, editor, clinician.

We talk about writing with Danielle Ofri, editor of the Bellevue Literary Review, author of “Singular Intimacies: Becoming a Doctor at Bellevue” and “Incidental Findings: Lessons from My Patients in the Art of Medicine,” and an attending physician at Bellevue. I figured you could do with less information about influenza. If you’ve got a reaction, call […]


March 13th, 2009

Podcast 34: An interview with Cheryl Bushnell of Wake Forest about her paper in BMJ concerning migraines during pregnancy and the possibility of their relation to strokes and other vascular problems.

BMJ‘s paper on the possible association of migraine during pregnancy and stroke (and other vascular problems) is the focus of this week’s interview. We speak with first-author Dr. Cheryl Bushnell. And then there’s the week’s news, plus a message from a listener! It could have been you, if only you’d called 1-617-440-4374 and made a […]


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