Posts Tagged ‘nephropathy’

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May 2nd, 2010

Podcast 85: B vitamins lower homocysteine levels, so why don’t they retard the progression of diabetic nephropathy?

A surprise finding: homocysteine is supposed to be a factor in vascular inflammation, but lowering hyperhomocysteinemia in patients with diabetic nephropathy actually accelerated the decline of  their GFRs. What gives? We have a conversation with Dr. J. David Spence, whose results were just published in JAMA. Interview-related link: JAMA paper on the effect of B vitamins on diabetic […]


February 19th, 2010

Podcast 75: Which regimen for hypertension?

Patients with hypertension at risk for cardiovascular events have done better with an ACE inhibitor-calcium channel blocker combination than with the ACE inhibitor plus hydrochlorothiazide. The ACCOMPLISH investigators have now reported on their analysis of progression-of-nephropathy outcomes in their trial. We interview the first author of the analysis, Dr. George Bakris of the University of […]


July 2nd, 2009

Podcast 48: A conversation with Les Irwig, which your bone scanner won’t like to hear.

Scanning patients on bisphosphonates within the first 3 years of therapy is just wasted effort, and may even be misleading clinically. That’s what researchers conclude after reanalysis of FIT trial data on some 6500 women taking either alendronate or placebo. Prof. Les Irwig of the University of Sydney talks about his team’s findings and what […]


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