April 10th, 2018
Podcast 221: Pertussis makes a comeback — kids have an outsize role
What’s causing this resurgence, and what’s to be done? Pejman Rohani talks about his Science Translational Medicine study that used “gold standard” historical data to examine possible causes. He and his colleagues conclude that, as with mumps, slowly waning vaccine protection is at play. However, they identify the “core transmission group” as schoolchildren, who have a […]
June 12th, 2015
Podcast 176: HPV Vaccine — How many doses are needed to confer protection?
Running time: 19 minutes We talk with Dr. Cosette Wheeler about a new Lancet Oncology paper that offers follow-up on two major trials of HPV-16/18 vaccines. The analysis adds more data to the suspicion that although three doses of vaccine are optimal, two or even one may offer substantial protection. Wheeler is very cautious on this point, […]
April 14th, 2012
Podcast 151: Most people above age 10 have at least some cross-reactive antibodies to variant influenza
Influenza A (H3N2)v — a novel flu virus that emerged last summer and shows signs of being able to transmit itself from person to person — is our topic this week. The virus carries genes from swine and avian flu viruses, and the few cases found in the U.S. all made complete recovery. We talk with CDC […]
October 28th, 2011
Podcast 135: HPV vaccine effective against anal intraepithelial neoplasia in MSM. Now, how to get it to young men before they’re sexually active?
The quadrivalent HPV vaccine was effective at preventing anal intraepithelial neoplasias in men who have sex with men, it was reported last week. The larger question is how to get it to young men before they become sexually active. We interview Dr. Joel Palefsky of UCSF, the first author on a paper in the New England Journal […]
September 23rd, 2011
Podcast 131: Measuring the effect of the rotavirus vaccine program on kids in the U.S.
Vaccines work, and here’s more evidence. The quadrivalent rotavirus vaccine introduced in 2006 has dramatically lowered hospitalizations for rotavirus-related diarrhea among children under age 5, among other benefits. Its presence has produced a kind of herd immunity whereby even the unvaccinated are reaping benefits. It bears remembering, though, that vaccinees have about a 90% lower […]
September 10th, 2010
Podcast 100: Practical informed consent
We’re not talking about philosophy here, but practical clinical approaches to making sure your patients understand what they’re agreeing to, and have the information to ask the right questions before they sign that form. It’s podcast 100. I’m always looking for ways to make this useful, and if you have any reactions, please drop a line […]
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