Articles matching the ‘aspirin’ Category

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March 9th, 2018

Podcast 217: Aspirin and rivaroxaban “comparably effective and safe” for prophylaxis after arthroplasty

The EPCAT II trial examined whether aspirin and rivaroxaban were clinically equivalent in the extended prophylaxis of venous thromboembolism after hip or knee replacement. They proved “comparably effective and safe,” according to our guest, Dr. David Anderson, the study’s first author. An editorial in the New England Journal of Medicine, where the study appeared […]


May 2nd, 2012

Podcast 154: Treating heart failure’s hypercoagulable state — warfarin or aspirin?

Heart failure brings problems associated with hypercoagulation, such as stroke and sudden death. An international study followed some 2300 patients with heart failure (ejection fractions of 35% or less) and in stable sinus rhythm for a mean of 3.5 years, randomizing them to treatment with either warfarin or aspirin. The two treatment groups showed about the […]


November 4th, 2011

Podcast 136: Aspirin lowers colorectal risks in Lynch syndrome — what are the implications for everyone else?

Last week’s Lancet article on the effect of aspirin on risks for colorectal cancer in patients with Lynch syndrome — a group at particularly high risk — may hold implications for preventing sporadic colon cancers. Our interview with Prof. Sir John Burn, the study’s first author, explores those implications as well speculations on why  we […]


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