Recent Posts

February 20th, 2009

Podcast 31: Making your clinical life easier — with genetics. Dr. Julie Johnson talks about using a patient’s genetic profile to help set their initial warfarin dose more accurately. You got a problem with that?

Starting a patient on warfarin is nobody’s idea of a good time, but pharmacogenetic research can help. A study in this week’s NEJM shows the advantage of using genetic information (plus some clinical data) over the old “start at 5 mg a day and pray for success” approach. We talk with Julie Johnson of the University of Florida about the study.

We’ve shortened our news presentation, on the theory that you can’t assimilate too many details through your ears, so we give you the aural cartoon version and provide links for details at the website: podcasts.jwatch.org.

If you want to contact us with your suggestions, please call 1 617 440 4374.

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February 16th, 2009

Podcast 30: Dr. Roger Chou of Oregon Health Sciences University talks about recent guidelines for opioid use in non-cancer pain and reflects on the FDA’s recent announcement of tighter regulation on use of the drugs.

The FDA announced an early-March meeting with manufacturers of opioids to discuss how problems with the drugs’ overuse and abuse might be addressed. We talk with an author of guidelines just published (and freely available) in the Journal of Pain that coincidentally address some of these concerns.

Then, of course, there’s the usual news roundup, and we finish off with a 200th birthday salute to Charles Darwin (no thanks to unevolved Americans).

To join the merriment or complain about the cake, call 617-440-4374 and leave a message.

To trace the evolution of “Admitting Diagnosis,” which we admit is horribly misnamed, go to podcasts.jwatch.org.

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February 8th, 2009

Podcast 29: Dr. Brian Jack of Boston University sees RED (Re-Engineered Discharge) as a way to lower hospital readmissions.

Millions of people are discharged each year from U.S. hospitals. How many find themselves on the street with no clear idea of what they’ve been treated for, what drugs they should take and when, and how to get in touch with a clinician if something goes wrong?

No surprise, many are readmitted — either directly or through the emergency room.

Brian Jack and colleagues embarked on Project RED to re-engineer hospital discharge procedures (which, by the way, are not currently standardized).

There’s news and links too. Plus, your chance to talk back by calling 617-440-4374.

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January 30th, 2009

Podcast 28: A discussion with Dr. Andrea Cipriani and Prof. John Geddes about their ranking of 12 antidepressants

There are a dozen new-generation antidpressants on the market now. How to sort them out? On what basis? We talk with two authors of an intriguing meta-analysis released online in Lancet this week.

And we offer the usual roundup of news and, speaking of roundups, a working name while we come up with something better than the rather staid “Admitting Diagnosis.”

Calls, comments, and complaints to 1-617-440-4374.

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January 25th, 2009

Podcast 27: Dr. Steven E. Sobol talks with us about his paper on trends in pediatric head-and-neck infections from S. aureus — an increasing percentage of which are MRSA.

The 6-year period 2001 – 2006 saw an increase from 12 to 28 in the percentage of S. aureus infections among head-and-neck infections in childen that were methicillin resistant. This 16-point jump is concerning, and we talk with an author of the paper documenting that increase.

Also, we’d like to know: should we be calling this thing here “Admitting Diagnosis” — or something else?

If you would like to comment or offer an idea for a future podcast, please call 617-440-4374.

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January 18th, 2009

Podcast 26: Dr. Wayne A. Ray talks about the dangers of sudden cardiac death from antipsychotic drugs

NEJM published a paper this week detailing the risks of sudden cardiac death in those taking both typical and atypical antipsychotic drugs. We talk with the paper’s first author Dr. Wayne A. Ray of Vanderbilt University School of Medicine.

If you would like to comment or offer an idea for a future podcast, please call 617-440-4374.

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