Articles matching the ‘meta-analysis’ Category

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August 2nd, 2019

Podcast 227: Chronic kidney disease and anticoagulants

Chronic kidney disease, being a “prothrombic state,” would seem to warrant use of anticoagulants, yet they aren’t often used — why? The problem seems to be a lack of data with which to evaluate their effectiveness and possible harms. Big drug trials seem to avoid recruiting these patients, especially those in the later stages of […]


September 14th, 2017

Podcast 212: BP in CKD — Where’s the Sweet Spot?

There was an excellent commentary accompanying a recent JAMA Internal Medicine meta-analysis: “The Ideal Blood Pressure Target for Patients with Chronic Kidney Disease — Searching for the Sweet Spot” by Csaba Kovesdy. He offers a nice perspective on the problem and kindly agreed to talk with us. Links: Kovesdy’s commentary in JAMA Internal Medicine The meta-analysis […]


January 30th, 2009

Podcast 28: A discussion with Dr. Andrea Cipriani and Prof. John Geddes about their ranking of 12 antidepressants

There are a dozen new-generation antidpressants on the market now. How to sort them out? On what basis? We talk with two authors of an intriguing meta-analysis released online in Lancet this week. And we offer the usual roundup of news and, speaking of roundups, a working name while we come up with something better […]


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