Recent Posts

August 14th, 2010

Podcast 97: What happens when vena cava filters break?

Vena cava filters, often meant to be permanent, can actually lose a strut or two. And it’s not as rare an occurrence as you might think. Our conversationalist found it happens about 15% of the time with a certain brand of filter. The FDA has announced that it’s starting its own studies of the problem. Listen in.

If you see something during the week that you’d like me to devote an interview to, please let me know. My email is jelia@jwatch.org. I’d love to have your suggestions.

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July 30th, 2010

Podcast 96: Survivors of childhood cancer face manageable reproductive risks.

What becomes of children who survive cancer treatment and enter their reproductive years? Would their attempts to have children end in a higher-than-normal rate of stillbirths and miscarriages? Apparently not.

It turns out the major concern is with women who’ve undergone pelvic irradiation before menarche. That treatment seems to hobble uterine development, but not irretrievably. For their part, boys who’ve had gonadal irradiation seem not to place their offspring at higher risk for adverse birth outcomes.

Our conversation is with the senior author on a Lancet paper from last week investigating these effects.

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July 9th, 2010

Podcast 95: What if hypertensive patients titrated their own drug dosages?

This week’s interview is with the editorialist commenting on an exciting Lancet paper. The writer, Dr. Gbenga Ogedegbe, says that the work, in which patients with uncontrolled hypertension titrated their own medications according to prespecified rules, could change how clinicians manage uncomplicated hypertension. From his base at New York University School of Medicine, Dr. Ogedegbe sees promise — if the costs are right. Listen in.

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July 1st, 2010

Podcast 94: What does a new meta-analysis tell us about statins and primary prevention?

A meta-analysis of 11 studies encompassing more than 60,000 subjects finds that statins don’t lower all-cause mortality in people without cardiovascular disease. One editorialist calls the study, just published in the Archives of Internal Medicine, “the cleanest and most complete meta-analysis of pharmacological lipid lowering for primary prevention.”

One of the study’s principal authors, Kausik K. Ray, talked with us from London. I think you’ll find that listening in is worth your time.

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June 25th, 2010

Podcast 93: Is computed tomography safe? Yes, but …

That’s the question asked in an intriguing essay — by a radiologist — released online in the New England Journal of Medicine. We have her as our guest this week.

Feedback, please! You can comment here or by emailing me at jelia@jwatch.org — or better still, call 1-617-440-4374.

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June 18th, 2010

Podcast 92: Corticosteroids in COPD exacerbations — high-dose intravenous or low-dose oral?

A JAMA paper suggests that in all but the most severe exacerbations of COPD, it’s best to start off with low-dose oral corticosteroids rather than the higher-dose intravenous treatment that, contrary to guideline recommendations, almost everyone now gets. Our conversation this week is with the study’s first author, Dr. Peter Lindenauer.

Visit the Journal Watch website at http://jwatch.org for a comprehensive look at new medical research, with comments from our experts.

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