July 11th, 2015
Podcast 179: Pradaxa (dabigatran) reversal near?
Running time: 20 minutes The anticoagulant dabigatran, marketed in the U.S. as Pradaxa, has always had the problem that, although it’s more convenient to use, there’s no sure way to stop its effect if the patient has a major bleed. Now, a monoclonal antibody fragment called idarucizumab (pronounced i-DARE-you-scis-ooh-mab) shows promise as a reversal agent. In an […]
May 2nd, 2012
Podcast 154: Treating heart failure’s hypercoagulable state — warfarin or aspirin?
Heart failure brings problems associated with hypercoagulation, such as stroke and sudden death. An international study followed some 2300 patients with heart failure (ejection fractions of 35% or less) and in stable sinus rhythm for a mean of 3.5 years, randomizing them to treatment with either warfarin or aspirin. The two treatment groups showed about the same […]
March 10th, 2011
Podcast 115: Talking about the real-world use of dabigatran with Drs. Elaine Hylek and Samuel Goldhaber
Clinical Conversations, in a collaboration with CardioExchange, has interviewed two expert working clinicians on how best to use dabigatran — a drug poised to supplant warfarin in the prevention of stroke and systemic embolism in patients with atrial fibrillation. The wide ranging discussion with Drs. Elaine Hylek and Samuel Goldhaber includes sections on who should be […]
November 19th, 2010
Podcast 109: An overview of the American Heart Association meeting, with cardiologist Harlan Krumholz
We’ve got Dr. Harlan Krumholz, editor of Journal Watch Cardiology and CardioExchange, to guide us through a week’s worth of the top research presented at the American Heart Association in Chicago. Interview-related links (in the order we discuss them in the interview): CardioExchange (worth checking out — it’s an experiment in the clinical use of social media) […]
April 16th, 2010
Podcast 83: An interview by CardioExchange’s editors on the COURAGE study
This week’s conversation introduces you to CardioExchange, a joint effort by Journal Watch and the New England Journal of Medicine to create an online community of clinicians interested in cardiovascular diseases. Two of CardioExchange’s editors, Dr. Richard Lange and Dr. L. David Hillis, interview Dr. William Boden of the COURAGE study, and Dr. Gregg Stone, an […]
September 4th, 2009
Podcast 55: A conversation with Prof. Gilles Montalescot about his JAMA paper on immediate versus delayed intervention in non-ST-segment elevation acute coronary syndrome
French researchers find that in non-ST-elevation acute coronary syndrome, delaying intervention until the next day does not affect the occurrence of death, MI, or the need for urgent revascularization by the one-month mark. We caught up with the study’s first author in Paris. If you want access to earlier podcasts, you’ve come to the right […]
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