April 22nd, 2011
Podcast 119: Calcium supplements and risk
Most clinicians, when asked, say they will routinely recommend calcium supplements for their postmenopausal patients. A meta-analysis from BMJ shows that this well-intentioned advice seems to lead to a moderate increase in cardiovascular risk in these women. We talk with Prof. Ian Reid, whose re-analysis of Women’s Health Initiative data confirms earlier work he’d done. Listen in. […]
March 27th, 2010
Podcast 80: Bisphosphonates and atypical hip fractures — how large is the risk?
We talk with three of the academic authors of a New England Journal of Medicine study that pooled data from a few studies in an attempt to examine the possible link between use of bisphosphonates and femoral-shaft fractures. Interview-related links: Physician’s First Watch coverage NEJM paper NEJM editorial FDA statement News-related links: Aspirin ineffective in preventing miscarriage BNP-guided […]
July 2nd, 2009
Podcast 48: A conversation with Les Irwig, which your bone scanner won’t like to hear.
Scanning patients on bisphosphonates within the first 3 years of therapy is just wasted effort, and may even be misleading clinically. That’s what researchers conclude after reanalysis of FIT trial data on some 6500 women taking either alendronate or placebo. Prof. Les Irwig of the University of Sydney talks about his team’s findings and what […]