February 21st, 2020
Podcast 253: Is a single-dose HPV vaccination effective?
With human papillomavirus vaccine in short supply around, moving from a three- or two-dose regimen to one dose would immediately double or treble supplies, cut costs, and simplify logistics. A careful study in Cancer by this week’s guest, Ana Rodriguez, and her colleagues adds to the evidence that single-dosing is possible and protective against pre-cancerous cervical lesions. […]
April 30th, 2012
Podcast 153: Type 2 diabetes in young people — tough going on the treatment front
About half of adolescents with type 2 diabetes fail treatment with metformin alone within a few years. Things go somewhat better with metformin plus an intensive lifestyle intervention, and better still with the addition of rosiglitazone to metformin — however even the addition of the second drug leads to treatment failure about 40% of the time. […]
August 14th, 2010
Podcast 97: What happens when vena cava filters break?
Vena cava filters, often meant to be permanent, can actually lose a strut or two. And it’s not as rare an occurrence as you might think. Our conversationalist found it happens about 15% of the time with a certain brand of filter. The FDA has announced that it’s starting its own studies of the problem. […]
February 20th, 2009
Podcast 31: Making your clinical life easier — with genetics. Dr. Julie Johnson talks about using a patient’s genetic profile to help set their initial warfarin dose more accurately. You got a problem with that?
Starting a patient on warfarin is nobody’s idea of a good time, but pharmacogenetic research can help. A study in this week’s NEJM shows the advantage of using genetic information (plus some clinical data) over the old “start at 5 mg a day and pray for success” approach. We talk with Julie Johnson of the […]
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