June 9th, 2016
Podcast 203: What’s wrong with guidelines
Download the TRANSCRIPTION_JWPodcast203 We talk with Dr. Margaret McCartney of Glasgow about her essay in The BMJ. She and her three co-authors titled it “Making Evidence-Based Medicine Work for Individual Patients.” Note: We’re going to start including transcripts, and may even add transcripts to earlier podcasts. Let me know your reactions at jelia@nejm.org. BMJ essay Transcript of Podcast 203 Guest: […]
May 12th, 2016
Podcast 202: Disaster Medicine — a New Edition
Drs. Kristi Koenig and Carl Schultz have just published a second edition of their textbook Disaster Medicine: Comprehensive principles and practices. And they do mean comprehensive. The book runs some 750 pages, covering everything from ethics (not so different from “normal” ethics, it turns out) to managing mass gatherings (a nice guide is provided), tornadoes, volcanoes, […]
August 7th, 2015
Podcast 181: Oral Contraceptives’ Role in Reducing Endometrial Cancers
(Running time: 15 minutes) A study in the Lancet Oncology gathered information from dozens of epidemiological studies to estimate that over 200,000 cases of endometrial cancer have been prevented in the past 10 years as a result of oral contraceptive use. A commentary in the journal offers a remarkable look at weighing the benefits and harms of OCs. […]
July 11th, 2015
Podcast 179: Pradaxa (dabigatran) reversal near?
Running time: 20 minutes The anticoagulant dabigatran, marketed in the U.S. as Pradaxa, has always had the problem that, although it’s more convenient to use, there’s no sure way to stop its effect if the patient has a major bleed. Now, a monoclonal antibody fragment called idarucizumab (pronounced i-DARE-you-scis-ooh-mab) shows promise as a reversal agent. In an […]
June 22nd, 2015
Clinical Conversation 177: Can We Deliver NICEly?
Neel Shah wrote a Perspective essay in the New England Journal of Medicine earlier this month on the U.K.’s NICE recommendation that encourages wider acceptance of home delivery and midwifery. The question is, could it work in the U.S.? For the audio-oriented Clin Con audience we’ve adapted a video conversation that took place on Medstro (https://medstro.com/groups/nejm-group-open-forum/discussions/112). […]
June 12th, 2015
Podcast 176: HPV Vaccine — How many doses are needed to confer protection?
Running time: 19 minutes We talk with Dr. Cosette Wheeler about a new Lancet Oncology paper that offers follow-up on two major trials of HPV-16/18 vaccines. The analysis adds more data to the suspicion that although three doses of vaccine are optimal, two or even one may offer substantial protection. Wheeler is very cautious on this point, […]
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