Clinical Conversations

August 20th, 2017

Podcast 211: On (not) staying the (antibiotic) course

Sometimes — but not all the time — patients can be advised to stop a course of antibiotics if they feel better. Traditionally, the advice has been to complete the entire course, regardless. Why? Because it was thought that stopping early might lead to more antibiotic resistance. That’s changing now, as the WHO and the […]

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March 4th, 2016

Podcast 197: A dissent on sepsis

The authors of the new sepsis definitions encouraged “debate and discussion,” and an editorial in Chest was quick to provide it. The editorialist, Dr. Steven Simpson, is worried about missing some cases if consideration of SIRS (the systemic inflammatory response syndrome) is tossed out of the definition. Chest editorial (free PDF available if you scroll down that landing page) […]

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February 27th, 2016

Podcast 196: Sepsis redefined

We have Edward Abraham, Dean of Wake Forest School of Medicine, with us to talk about the new definitions of sepsis and septic shock. He wrote an editorial in JAMA that puts the changed definitions into perspective for clinicians. Listen in. Editorial in JAMA (free) JAMA paper with new definitions (free) NEJM Journal Watch coverage (free)  

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