September 4th, 2009
Podcast 55: A conversation with Prof. Gilles Montalescot about his JAMA paper on immediate versus delayed intervention in non-ST-segment elevation acute coronary syndrome
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French researchers find that in non-ST-elevation acute coronary syndrome, delaying intervention until the next day does not affect the occurrence of death, MI, or the need for urgent revascularization by the one-month mark. We caught up with the study’s first author in Paris.
If you want access to earlier podcasts, you’ve come to the right place if you’re reading this at http://podcasts.jwatch.org. If you’d like to leave a note of delight or dismay, 1-617-440-4374 is the place to do so — or via email to me at jelia@nejm.org.
This week’s news and interview links:
- Immediate vs. Delayed Intervention in Non-ST-Segment Elevation ACS
- 2009 H1N1 Update: Childhood Deaths; Two-Dose Vaccine Likely; N95 Respirators
- Nonsurgical Treatment for Dupuytren Contracture with Collagenase
- Dabigatran at Least as Effective as Warfarin in Patients with Afib
- Ticagrelor Superior to Clopidogrel in Patients with Acute Coronary Syndromes
August 21st, 2009
Podcast 54: A conversation with Aaron Caughey, whose analysis of the literature shows that elective induction of labor does not, contrary to dogma, increase the risk of cesarean delivery.
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Well, the headline says it all. UCSF’s Aaron Caughey has just published a meta-analysis in Annals of Internal Medicine that shatters the dogma of elective induction’s being associated with cesarean delivery. I hope you’ll enjoy the conversation.
There won’t be a Clinical Conversation next week — I’m taking a week off — but the chit-chat returns in two weeks.
Older conversations are all archived here at podcasts.jwatch.org, and you can leave me a note at 1-617-440-4374 or at jelia@nejm.org.
This week’s links:
- Supervised Heroin Treatment Outperforms Methadone in Refractory Users
- FDA Approves Hiberix as Haemophilus Vaccine Booster Dose
- HPV Vaccine About as Safe as Other Vaccines, Researchers Report
- Chinese Herb Appears Better Than Standard Treatment for Rheumatoid Arthritis
The Interview’s story link:
August 14th, 2009
Podcast 53: Patients extubated with hypercapnia can be managed better with noninvasive ventilation, a new study shows.
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Dr. Miquel Ferrer of the University of Barcelona took some time away from his holiday to talk with us about an article he’s just published in Lancet. His research shows that in a subgroup of patients with chronic respiratory diseases (mostly COPD) who are undergoing extubation but who remain in hypercapnia, noninvasive ventilation support is the way to go.
This week’s links:
August 9th, 2009
Podcast 52: Screening for intimate-partner violence doesn’t seem productive or very protective. What’s a concerned clinician to do?
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We talk with two authors of a JAMA study that indicates that such screening doesn’t accomplish the ultimate goal: protecting the patient from further abuse. Our guests have some advice.
This week’s news links:
- Vertebroplasty No Better Than Sham Procedure in Osteoporotic Fractures
- Researchers Advise Labor Induction for Women with Mild Hypertensive Disease Late in Pregnancy
- TNF-Blockers to Carry New Cancer Warnings
Interview links:
July 31st, 2009
Podcast 51: In pregnant women with suspected H1N1, treat promptly! A conversation with Denise Jamieson of the CDC.
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It’s simple: pregnant women (for un-simple reasons) are at greater risk for flu complications. It’s true even among hitherto apparently healthy patients. We’ve got a conversation with a CDC researcher who’s just published a paper in Lancet that urges prompt treatment, even in the face of pending lab results, with antivirals. Contact us at 1-617-440-4374.
This week’s links:
- ACIP Recommends Five Groups as Priority Targets for H1N1 Vaccination
- In Pregnancy, Treat Suspected H1N1 Promptly Without Awaiting Test Results
- CDC “Full-Out” Recommends Seasonal Flu Vaccination for Children Over 6 Months
- Expensive Tests to Evaluate Syncope Don’t Yield as Much as Simple Postural BP
- ACOG Revises Labor Induction Guidelines
July 19th, 2009
Podcast 50: A re-podcast of an interview from February regarding the FDA’s plans for tightening regulations on opioid use.
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This week the FDA approved a form of fentanyl that can be administered through the buccal mucosa — but its label carries boxed warnings. And two weeks ago, the opioid propoxyphene got boxed warnings on its Darvon and Darvocet formulations. The FDA is trying to regulate the opioids more closely, reminding prescribers and users of the dangers they pose. In February, after another FDA announcement on opioid control, we interviewed Dr. Roger Chou of Oregon Health Sciences University on this topic.
Since it’s summer and the news is relatively scant, I’m reprising the interview and skipping the news summary.
Enough said!
This week’s links:
- Darvon, Darvocet to Get Stronger Warnings on Fatal Overdose Risk
- FDA Approves Fentanyl Buccal Soluble Film
Older links:
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