Clinical Conversations

 

 Standard Podcast: Play Now | Play in Popup | Download

There are consequences of even short-term use of some drugs. Take the second-generation antipsychotics. A 3-month course can cause weight gain of almost 20 pounds in young people, according to a JAMA study. We interview Dr. Christoph Correll about the implications.

To reach Clinical Conversations, you can call 1-617-440-4374 or email me at jelia@jwatch.org.

This weeks news and interview links:

News:

• Diabetes Prevention Interventions Have Long-Lasting Effects

• Antibiotic Prophylaxis Lowers Risk for UTIs in Predisposed Kids

• (Some of) You Are Feeling Very Sleepy…

Interview:

• Atypical Antipsychotics Associated with Weight Gain and Other Adverse Metabolic Effects in Kids

 

 Standard Podcast: Play Now | Play in Popup | Download

The FDA seems set to announce a decision about vaccinating women past age 25 for HPV. A paper in the Annals of Internal Medicine this week indicates that such a strategy wouldn’t be cost-effective.

Don’t be put off by “cost-effectiveness” or by the fact that we actually discuss “QALY”s. It’s all good. We’ve got Harvard School of Public Health’s Jane Kim to guide your interviewer through the QALY thicket, and she’s a great guide.

Contact us at 1-617-440-4374 or write to jelia@nejm.org.

This week’s links:

NEWS:

• Aldosterone Antagonists Underused in Heart Failure

• ACP Issues Guidelines on Hormonal Testing and Pharmacologic Management of Erectile Dysfunction

• Ketorolac for Injection Recalled

• Intensified BP Control Benefits Kids with Chronic Kidney Disease

INTERVIEW:

• Adding HPV Vaccination to U.S. Cervical Screening Isn’t Cost-Effective After Age 30

 

 Standard Podcast: Play Now | Play in Popup | Download

We talk with Susan Mitchell, a Harvard researcher who set out to characterize the final clinical stages of advanced dementia. There are some surprises — namely, the benefit of clear communications with patients and their families (which, come to think of it, shouldn’t come as much of a surprise at all).

Talk with us at 1-617-440-4374 or write to jelia@nejm.org.

This week’s links:

Interview:

• Advanced Dementia’s Course

News summaries:

• Prophylactic Acetaminophen Reduces Immunogenicity of Childhood Vaccines

• Nursing Home Residents See Marked Declines in Functional Status After Starting Dialysis

• Minimally Invasive vs. Open Radical Prostatectomy