Clinical Conversations

 

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Investigators have suspected that there isn’t much advantage to renovascular angioplasty and stenting in atherosclerosis, but their studies haven’t had the statistical power to prove that point. A new bit of research in this week’s New England Journal of Medicine may have hit the mark. We’ve got an interview with two of the principals of the ASTRAL study (that’s their acronym for Angioplasty and Stenting for Renal Artery Lesions). Dr. Philip Kalra, the nephrology lead, and Dr. Jonathan Moss, the radiology lead, kindly agreed to the conversation, which I think you’ll find of interest.

Reach us with your comments and suggestions at jelia@jwatch.org, or call 1-617-440-4374.

This edition’s links:

Interview link–

• No Clinical Benefits of Revascularization in Atherosclerotic Renal Arteries

News links–

• H1N1 Update: Estimates of Flu’s Toll; Seasonal Vaccine Not Effective Against 2009 H1N1
• Prone Position for Acute Respiratory Distress Syndrome Doesn’t Boost Survival

 

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Avoiding use of the heart-lung machine during coronary artery bypass grafting was supposed to lower neurocognitive problems and other complications after the procedure. A large randomized trial finds otherwise. We’ve got a conversation with one of the investigators, Frederick Grover.

To contact us, call 1-617-440-4374. You can write to me at jelia@jwatch.org.

This week’s links:

News links:

• Primary Care Visit Length Increasing

• H1N1 Update: CDC Releases ‘Quick Facts’ for Providers on Antiviral Drug Use

• Aspirin for Primary Prevention ‘Should Not Be Routinely Initiated’

Interview links:

• Coronary Artery Bypass Grafting: On Pump or Off Pump?

 

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There are consequences of even short-term use of some drugs. Take the second-generation antipsychotics. A 3-month course can cause weight gain of almost 20 pounds in young people, according to a JAMA study. We interview Dr. Christoph Correll about the implications.

To reach Clinical Conversations, you can call 1-617-440-4374 or email me at jelia@jwatch.org.

This weeks news and interview links:

News:

• Diabetes Prevention Interventions Have Long-Lasting Effects

• Antibiotic Prophylaxis Lowers Risk for UTIs in Predisposed Kids

• (Some of) You Are Feeling Very Sleepy…

Interview:

• Atypical Antipsychotics Associated with Weight Gain and Other Adverse Metabolic Effects in Kids