Posts Tagged ‘hypertension’


November 9th, 2015

Podcast 189: Blood Pressure Target Should Be 120, SPRINT Data Show

The SPRINT study, suggesting that we aim for a systolic BP target of 120 mm Hg in high-risk hypertensive patients, has been published with much fanfare. Dr. Paul Whelton — one of the SPRINT investigators — is our guest. He warns against setting 120 as a performance measure, observing that roughly half the patients in […]

November 1st, 2015

Podcast 188: Should “deintensification” be a quality-of-care measure?

The ACCORD trial found dangers in too-strict control of blood pressure and glucose in diabetes. Our guest has just published a study in JAMA Internal Medicine measuring the scope of the problem. Using Veterans Affairs data, his group found that “deintensification” of therapy after targets were met or exceeded was disappointingly rare. JAMA Internal Medicine […]

August 29th, 2014

Podcast 173: Sensible Sodium Levels in View at Last

Running time: 9 minutes In the light of the New England Journal of Medicine‘s recent publication three papers on sodium intake and its implications for cardiovascular disease, blood pressure, and excess mortality, we thought we’d speak again with Dr. Jan Staessen, who surprised a lot of people 3 years ago with a paper in JAMA […]

September 14th, 2013

Podcast 167 — The polypill: adherence at last?

Running time: 7 min The recent JAMA article examining the effects of the “polypill” on adherence and clinical benefits in patients with (or at high risk for) cardiovascular disease, is our topic. The polypill in this trial contained fixed doses of four separate drugs: aspirin, a statin, lisinopril and one other blood-pressure-lowering drug — either […]

December 17th, 2011

Podcast 139: CPAP for obstructive sleep apnea seems to improve some measures of the metabolic syndrome

A double-blind crossover study in the New England Journal of Medicine shows that 3 months of continuous positive airway pressure (CPAP) in patients with moderate to severe obstructive sleep apnea ameliorates some components of the metabolic syndrome, which is present in about three quarters of such patients. The authors acknowledge the difficulty of motivating patients […]

June 25th, 2011

Podcast 124: Getting more accuracy into blood pressure measurements

Patients’ systolic pressures vary by about 10%, regardless of whether they are measured at home or under the duress of a visit to the doctor. That variation is troubling when deciding whether to put a patient on an antihypertensive regimen: how reliable are the measurements that will form the basis of your decision? How […]

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