Posts Tagged ‘Diabetes type 2’

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February 18th, 2016

Podcast 195: Pioglitazone for secondary prevention?

Pioglitazone, long known to increase insulin sensitivity, has been “mostly relegated to use in unusual conditions such as lipodystrophies” after its drug class, the thiazolidinediones, “fell from grace” in the words of our guest. Dr. Clay Semenkovich has just written an editorial comment on a study in the New England Journal of Medicine. That […]


December 10th, 2015

Podcast 192: Are we too sweet on HbA1c testing?

Over half the patients with Type 2 diabetes have their HbA1c measured too frequently — i.e., at least three times a year. Why is that a bad thing? Dr. Rozalina McCoy, the lead author of a paper in The BMJ explains. Using claims data, her group followed over 30,000 patients with stable HbA1c levels and […]


April 30th, 2012

Podcast 153: Type 2 diabetes in young people — tough going on the treatment front

About half of adolescents with type 2 diabetes fail treatment with metformin alone within a few years. Things go somewhat better with metformin plus an intensive lifestyle intervention, and better still with the addition of rosiglitazone to metformin — however even the addition of the second drug leads to treatment failure about 40% of […]


March 15th, 2012

Podcast 149: High levels of white rice consumption seem linked to higher risks for type 2 diabetes

A BMJ meta-analysis suggests that people with the highest levels of white rice consumption are at increased risk for type 2 diabetes. The authors examined four studies, together comprising some 350,000 subjects. Two were done in Asian populations and two among Westerners. They found a much higher intake of white rice among Asians, and a […]


April 1st, 2011

Podcast 117: Atorvastatin and new-onset diabetes

Statins, according to a 2010 meta-analysis in Lancet, are associated with a slightly increased risk for new-onset type 2 diabetes. One, atorvastatin (marketed as Lipitor), was underrepresented in that analysis. Researchers, along with the manufacturer, decided to have a look at data from three trials to see whether atorvastatin also conferred that risk. And, […]


August 20th, 2010

Podcast 98: Leafy green vegetables apparently lower one’s risks for type 2 diabetes

Our interview this week is with a research nutritionist whose BMJ meta-analysis found a 14% reduction in risk for type 2 diabetes among those with the highest intake (versus those with the lowest) of leafy green vegetables. It’s a meta-analysis, and not a randomized controlled trial, and it’s interesting. Listen in. We’re off next week, […]


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