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Posts Tagged ‘Diabetes type 2’

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April 30th, 2012

Podcast 153: Type 2 diabetes in young people — tough going on the treatment front

About half of adolescents with type 2 diabetes fail treatment with metformin alone within a few years. Things go somewhat better with metformin plus an intensive lifestyle intervention, and better still with the addition of rosiglitazone to metformin — however even the addition of the second drug leads to treatment failure about 40% of [...]


March 15th, 2012

Podcast 149: High levels of white rice consumption seem linked to higher risks for type 2 diabetes

A BMJ meta-analysis suggests that people with the highest levels of white rice consumption are at increased risk for type 2 diabetes. The authors examined four studies, together comprising some 350,000 subjects. Two were done in Asian populations and two among Westerners. They found a much higher intake of white rice among Asians, and [...]


April 1st, 2011

Podcast 117: Atorvastatin and new-onset diabetes

Statins, according to a 2010 meta-analysis in Lancet, are associated with a slightly increased risk for new-onset type 2 diabetes. One, atorvastatin (marketed as Lipitor), was underrepresented in that analysis. Researchers, along with the manufacturer, decided to have a look at data from three trials to see whether atorvastatin also conferred that risk. And, [...]


August 20th, 2010

Podcast 98: Leafy green vegetables apparently lower one’s risks for type 2 diabetes

Our interview this week is with a research nutritionist whose BMJ meta-analysis found a 14% reduction in risk for type 2 diabetes among those with the highest intake (versus those with the lowest) of leafy green vegetables. It’s a meta-analysis, and not a randomized controlled trial, and it’s interesting. Listen in. We’re off next [...]


June 5th, 2010

Podcast 90: Preventing type 2 diabetes with low-dose metformin and rosiglitazone seems possible, but clinical use has to await results of another study.

Here’s a question wrapped in mist: How to prevent diabetes? Well, lifestyle changes for sure, but that’s hard. Drug therapy? Easier, but side effects can take away that advantage pretty quickly. Rosiglitazone offers some benefits, but its side effects — most notably increased risks for heart failure and death — have some people wondering [...]


April 2nd, 2010

Podcast 81: When should you start screening for type 2 diabetes?

A large-scale computer simulation based on NHANES data plotted the most cost-effective strategy, which turns out to be to start screening before middle age and to repeat every 3 to 5 years. We talk with the first author of a Lancet paper that details the findings. Interview-related link: Physician’s First Watch summary of the Lancet [...]


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