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Posts Tagged ‘Cardiovascular risk’

Podcast 152: Gum disease and atherosclerosis — evidence for an association, but not for a cause-and-effect

Joe Elia • April 18th, 2012

Categories: Atherosclerosis, Audio, Dentistry, Periodontal disease, Uncategorized

(2 votes, average: 3.00 out of 5)

The American Heart Association’s scientific statement on “Periodontal Disease and Atherosclerotic Vascular Disease” is likely to raise hackles among those offering treatments for gum disease as a way to lower risk for heart disease — or even to ameliorate it. The association’s writing committee, after a 4-year review of the evidence, finds no support [...]

Podcast 145: The Y chromosome and the possible role of a common variant in coronary disease in men.

Joe Elia • February 13th, 2012

Categories: Cardiovascular risk, Haplogroups, Uncategorized, Y chromosome

(4 votes, average: 4.75 out of 5)

Haplogroups — who knew? Ancient variations in the Y chromosome form what’s known as haplogroups, and haplogroup I is common in Europe, particularly so in northern Europe. Researchers find that “I” is an independent risk factor for coronary artery disease in men, carried as it is on the male-only Y chromosome. Listen in as [...]

Podcast 125: The smoking-cessation drug varenicline poses some difficult tradeoffs.

Joe Elia • July 8th, 2011

Categories: Audio, Smoking cessation, Uncategorized, Varenicline

(10 votes, average: 3.90 out of 5)

There is a new meta-analysis from the Canadian Medical Association Journal that finds increased risks among smokers trying to quit and taking varenicline (Chantix). Among smokers with stable cardiovascular disease, the number needed to treat to cause an adverse cardiovascular event is about 30, yet the number needed to treat to achieve smoking cessation [...]

Podcast 121: NSAIDs Unsafe at Any Dose after MI

Joe Elia • May 14th, 2011

Categories: Audio, Cardiovascular risk, NSAIDs, Uncategorized

(4 votes, average: 4.75 out of 5)

Guidelines warn about using NSAIDs after myocardial infarction, and a 10-year look-back study from Denmark shows that the warning should be even louder. Whereas current AHA guidelines advise using NSAIDs after MI for the briefest possible time, the Danish study, published last week in Circulation, finds that the risks for death and reinfarction begin [...]

Podcast 120: Pass the salt!

Joe Elia • May 6th, 2011

Categories: Audio, Cardiovascular risk, diet, Policy, Population studies, Salt, Uncategorized

(12 votes, average: 3.25 out of 5)

European researchers say they’ve got the data to show that restricting salt in the general population is a bad mistake. By implication, the U.S. dietary salt guidelines are plainly wrong. How did they do this? They followed 3700 subjects for roughly 8 years, having first measured their 24-hour urinary sodium excretion. Their data show [...]

Podcast 119: Calcium supplements and risk

Joe Elia • April 22nd, 2011

Categories: Audio, Cardiovascular risk, Osteoporosis, Patient care, Uncategorized

(6 votes, average: 4.00 out of 5)

Most clinicians, when asked, say they will routinely recommend calcium supplements for their postmenopausal patients. A meta-analysis from BMJ shows that this well-intentioned advice seems to lead to a moderate increase in cardiovascular risk in these women. We talk with Prof. Ian Reid, whose re-analysis of Women’s Health Initiative data confirms earlier work he’d [...]