Articles matching the ‘Uncategorized’ Category

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June 12th, 2015

Podcast 176: HPV Vaccine — How many doses are needed to confer protection?

Running time: 19 minutes We talk with Dr. Cosette Wheeler about a new Lancet Oncology paper that offers follow-up on two major trials of HPV-16/18 vaccines. The analysis adds more data to the suspicion that although three doses of vaccine are optimal, two or even one may offer substantial protection. Wheeler is very cautious on this […]


June 3rd, 2015

Podcast 175: “Understanding Value-Based Healthcare” — A Discussion with the Authors of an Important New Book

Running time: 26 minutes “Understanding Value-Based Healthcare,” published in April by McGraw-Hill is today’s focus. Drs. Christopher Moriates, of the University of California, San Francisco; Vineet Arora, of the University of Chicago; and Neel Shah of Harvard Medical — the book’s authors — discuss its straightforward approach to valuing patient outcomes foremost. The discussion ranges over their […]


September 9th, 2014

Podcast 174: PARADIGM and Heart Failure

The PARADIGM-HF trial of LCZ696 — a novel compound that both blocks the renin-angiotensin system with an ARB component and blocks neprilysin’s degradation of natriuretic peptides — increased survival in heart failure by some 20% relative to enalapril. It seems to be a big deal, and the trial’s two principal authors have agreed to […]


August 29th, 2014

Podcast 173: Sensible Sodium Levels in View at Last

Running time: 9 minutes In the light of the New England Journal of Medicine‘s recent publication three papers on sodium intake and its implications for cardiovascular disease, blood pressure, and excess mortality, we thought we’d speak again with Dr. Jan Staessen, who surprised a lot of people 3 years ago with a paper in JAMA […]


July 30th, 2014

Podcast 172: Listening for the Diagnosis, a Conversation with Danielle Ofri

Running time: 15 minutes Dr. Danielle Ofri, author and internist (as well as an aspiring cellist), is writing a book about how patients and clinicians hear each other. Our discussion centers on that, and on her request that you contact her if you can put her in touch with great diagnosticians (and maybe even their patients). […]


June 25th, 2014

Podcast 171: PTSD Treatment Effects Remain Largely Unmeasured By the Military and the VA

Running time: 10 minutes The Institute of Medicine’s report on treatment for post-traumatic stress disorder finds that active military and veterans with PTSD aren’t always getting evidence-based treatments. And when those treatments are used, they’re too often not used according to protocols and the results aren’t measured. The upshot? The agencies with responsibility for treating […]


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