Clinical Conversations

February 3rd, 2012

Podcast 144: Hip fractures, PPIs, and smoking history in postmenopausal women — increased risks

PPIs are back on our radar, and this time it’s their regular use among postmenopausal women. A BMJ article examines data from the Nurses’ Health Study to show a significantly increased risk for hip fracture among postmenopausal women with any smoking history. Never-smokers showed no statistically significant increase. Now that proton pump inhibitors have been available over-the-counter […]

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January 27th, 2012

Podcast 143: PPIs and asthma control — it doesn’t work in kids, either

Controlling asthma by the use of proton pump inhibitors apparently doesn’t work any better in children than it does in adults. Yet the practice is widely used. A study in JAMA and an accompanying fiery editorial seem to put the notion to rest. Listen in. As always, suggestions are welcomed. You can reach me directly at 617-440-4374 […]

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October 8th, 2010

Podcast 104: Reassurance on clopidogrel and omeprazole.

We welcome Dr. Danielle Bowen Scheurer to our conversational team this week She’s a hospitalist at the Medical University of South Carolina and an associate editor of Physician’s First Watch. Our guest is Dr. Deepak Bhatt, who has just published some reassuring results on omeprazole’s putative interaction with clopidogrel in the New England Journal of Medicine. If […]

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April 11th, 2009

Podcast 38: A conversation about using PPIs in poorly controlled asthma — rather, not using them — with Robert A. Wise of Johns Hopkins.

There are lots of people with poorly controlled asthma who are on PPIs, but don’t need to be. That’s the clear implication of research just published in the New England Journal of Medicine. We’ll talk with a member of the writing committee, Dr. Robert A. Wise. If you like what you hear, call 1-617-440-4374, and […]

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