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Archive for April, 2012

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April 30th, 2012

Podcast 153: Type 2 diabetes in young people — tough going on the treatment front

About half of adolescents with type 2 diabetes fail treatment with metformin alone within a few years. Things go somewhat better with metformin plus an intensive lifestyle intervention, and better still with the addition of rosiglitazone to metformin — however even the addition of the second drug leads to treatment failure about 40% of [...]


April 18th, 2012

Podcast 152: Gum disease and atherosclerosis — evidence for an association, but not for a cause-and-effect

The American Heart Association’s scientific statement on “Periodontal Disease and Atherosclerotic Vascular Disease” is likely to raise hackles among those offering treatments for gum disease as a way to lower risk for heart disease — or even to ameliorate it. The association’s writing committee, after a 4-year review of the evidence, finds no support [...]


April 14th, 2012

Podcast 151: Most people above age 10 have at least some cross-reactive antibodies to variant influenza

Influenza A (H3N2)v — a novel flu virus that emerged last summer and shows signs of being able to transmit itself from person to person — is our topic this week. The virus carries genes from swine and avian flu viruses, and the few cases found in the U.S. all made complete recovery. We [...]


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